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TitlePlant defense-directed discovery of a natural anti-psoriasis agent targeting GAPDH.
Journal, issue, pagesSci Adv, Vol. 11, Page eadw2578-eadw2578, Year 2025
Publish dateDec 18, 2024 (structure data deposition date)
AuthorsZhou, T.T. / Zheng, Y. / Zhang, M.W. / Gong, L.H. / Guo, K. / He, X.P. / Liu, Y.C. / Gershenzon, J. / Liu, Y. / Li, S.H.
External linksSci Adv / PubMed:40712011
MethodsX-ray diffraction
Resolution1.77 Å
Structure data

PDB-9l3e:
Structure of GAPDH complexed with Leu-F
Method: X-RAY DIFFRACTION / Resolution: 1.77 Å

Chemicals

PDB-1l6z:
CRYSTAL STRUCTURE OF MURINE CEACAM1A[1,4]: A CORONAVIRUS RECEPTOR AND CELL ADHESION MOLECULE IN THE CEA FAMILY

ChemComp-ZN:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / GAPDH / compound target

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