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TitleDe novo design and structure of a peptide-centric TCR mimic binding module.
Journal, issue, pagesScience, Vol. 389, Page 375-379, Year 2025
Publish dateDec 13, 2024 (structure data deposition date)
AuthorsHouseholder, K.D. / Xiang, X. / Jude, K.M. / Deng, A. / Obenaus, M. / Zhao, Y. / Wilson, S.C. / Chen, X. / Wang, N. / Garcia, K.C.
External linksScience / PubMed:40705894
MethodsX-ray diffraction
Resolution2.05 Å
Structure data

PDB-9min:
Structure of a designed minibinder to NYESO1-A*02:01
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
  • lama glama (llama)
KeywordsDE NOVO PROTEIN / complex / immune system

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