| タイトル | In vivo antibody diversification targeting a conserved coronavirus epitope. |
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| ジャーナル・号・ページ | J. Exp. Med., Vol. 222, Year 2025 |
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| 掲載日 | 2024年7月18日 (構造データの登録日) |
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著者 | Nair, U. / Feng, Z. / Akauliya, M. / Esposito, A.G. / Crain, C.R. / Lamperti, E.D. / Prum, T. / Warner, J.E. / Madungwe, L. / Dale, G.A. ...Nair, U. / Feng, Z. / Akauliya, M. / Esposito, A.G. / Crain, C.R. / Lamperti, E.D. / Prum, T. / Warner, J.E. / Madungwe, L. / Dale, G.A. / Boucau, J. / Gaiha, G.D. / Yuan, M. / Wilson, I.A. / Batista, F.D. |
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リンク | J. Exp. Med. / PubMed:40674170 |
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| 手法 | X線回折 |
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| 解像度 | 2.6 - 3.51 Å |
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| 構造データ | PDB-9cpp: Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies M22-17 and CC12.3 手法: X-RAY DIFFRACTION / 解像度: 3.19 Å PDB-9cpq: Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies M22-44 and CC12.3 手法: X-RAY DIFFRACTION / 解像度: 2.88 Å PDB-9cpr: Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies M22-90 and CC12.3 手法: X-RAY DIFFRACTION / 解像度: 3.1 Å PDB-9cps: Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies M22-91 and CC12.3 手法: X-RAY DIFFRACTION / 解像度: 3.03 Å PDB-9cpt: Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies M22-92 and CC12.3 手法: X-RAY DIFFRACTION / 解像度: 3.51 Å PDB-9cpu: Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C03-0304 and CC12.3 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å PDB-9cpv: Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C03-0614 and CC12.3 手法: X-RAY DIFFRACTION / 解像度: 3 Å PDB-9cpw: Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C11-1036 and CC12.3 手法: X-RAY DIFFRACTION / 解像度: 3.1 Å PDB-9cpx: Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C03-0138 and CC12.3 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-9cpy: Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C11-0860 and CC12.3 手法: X-RAY DIFFRACTION / 解像度: 3.1 Å |
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| 化合物 | |
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| 由来 |  severe acute respiratory syndrome coronavirus 2 (ウイルス) homo sapiens (ヒト) mus musculus (ハツカネズミ)
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キーワード | Viral Protein/IMMUNE SYSTEM / COVID-19 / SARS-CoV-2 / Receptor binding domain / Antibody / IMMUNE SYSTEM / Viral Protein-IMMUNE SYSTEM complex / IMMUNE SYSTEM/Viral Protein / IMMUNE SYSTEM-Viral Protein complex |
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