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Structure paper

TitleRevisiting the co-crystal structure of a DNA glycosylase with photocaged substrate: a suitable time-resolved crystallography target?
Journal, issue, pagesIucrj, Vol. 12, Page 515-522, Year 2025
Publish dateNov 14, 2024 (structure data deposition date)
AuthorsImura, T. / Hosokawa, Y. / Yang, K.C. / Ban, Y. / Shih, H.Y. / Yamamoto, J. / Maestre-Reyna, M.
External linksIucrj / PubMed:40658017
MethodsX-ray diffraction
Resolution2.48 - 2.81 Å
Structure data

PDB-9kky:
Co-crystal structure of human 8-oxoguanine glycosylase N149C mutant with DNA containing photocaged 8-oxoguanine
Method: X-RAY DIFFRACTION / Resolution: 2.81 Å

PDB-9kl8:
Co-crystal structure of human 8-oxoguanine glycosylase N149C mutant with DNA containing photocaged 8-oxoguanine after deprotection
Method: X-RAY DIFFRACTION / Resolution: 2.48 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLYASE / DNA-glycosylase / DNA repair / base excision repair / hOGG1 / photocaged / O6-(o-nitrophenisopropyl) 8-oxoguanine / deprotection of O6-(o-nitrophenisopropyl) 8-oxoguanine

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