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Structure paper

TitleStructural insights into a plant-conserved DHFR-TS reveal a selective herbicide target.
Journal, issue, pagesMol Plant, Vol. 18, Page 1294-1309, Year 2025
Publish dateJun 13, 2022 (structure data deposition date)
AuthorsHaywood, J. / Breese, K.J. / McDougal, D.P. / Verdonk, C. / Partridge, A. / Lo, A.F. / Zhang, J. / Yang, W.C. / Bruning, J.B. / Saliba, K.J. ...Haywood, J. / Breese, K.J. / McDougal, D.P. / Verdonk, C. / Partridge, A. / Lo, A.F. / Zhang, J. / Yang, W.C. / Bruning, J.B. / Saliba, K.J. / Bond, C.S. / Stubbs, K.A. / Mylne, J.S.
External linksMol Plant / PubMed:40598768
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-8dae:
Arabidopsis thaliana bifunctional dihydrofolate reductase-thymidylate synthase
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • arabidopsis thaliana (thale cress)
KeywordsTRANSFERASE / OXIDOREDUCTASE / apo

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