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TitleDe novo design of D-peptide ligands: Application to influenza virus hemagglutinin.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 122, Page e2426554122-e2426554122, Year 2025
Publish dateOct 12, 2024 (structure data deposition date)
AuthorsJuraszek, J. / Kadam, R.U. / Branduardi, D. / van Ameijde, J. / Garg, D. / Dailly, N. / Jongeneelen, M. / Vermond, J. / Brakenhoff, J.P.J. / Brandenburg, B. ...Juraszek, J. / Kadam, R.U. / Branduardi, D. / van Ameijde, J. / Garg, D. / Dailly, N. / Jongeneelen, M. / Vermond, J. / Brakenhoff, J.P.J. / Brandenburg, B. / van Dongen, M.J.P. / Vogels, R. / Friesen, R.H.E. / Wilson, I.A.
External linksProc. Natl. Acad. Sci. USA / PubMed:40577121
MethodsX-ray diffraction
Resolution2.37 Å
Structure data

PDB-9dxx:
Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with D-peptide
Method: X-RAY DIFFRACTION / Resolution: 2.37 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-TOE:
2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL

ChemComp-K:
Unknown entry

ChemComp-HOH:
WATER

Source
  • influenza a virus (a/puerto rico/8/1934(h1n1))
  • phage display vector pdvec0 (others)
KeywordsVIRAL PROTEIN / hemagglutinin / D-peptide

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