Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Optimization of Brain Penetrant SARM1 Orthosteric Inhibitors and Discovery of Their Paradoxical Subinhibitory Activation.
Journal, issue, pages	Acs Med. Chem. Lett., Vol. 16, Page 1147-1154, Year 2025
Publish date	Jan 16, 2025 (structure data deposition date)
Authors	Green, S.A. / Smith, R.T. / Grandner, J.M. / Zeng, M. / Del Bel, M. / Zhu, B.Y. / Liang, J. / Braun, M.G. / Sudhamsu, J. / Wallweber, H.A. ...Green, S.A. / Smith, R.T. / Grandner, J.M. / Zeng, M. / Del Bel, M. / Zhu, B.Y. / Liang, J. / Braun, M.G. / Sudhamsu, J. / Wallweber, H.A. / Boenig, G. / Murray, J. / Shen, X. / Zhang, R. / Lai, K.W. / Delwig, A. / Breboneria, M.A. / Ly, J. / Ganti, A. / Nespi, M. / Weber, M. / Leahey, R. / Hinz, F.I. / Chan, B.K.
External links	Acs Med. Chem. Lett. / PubMed:40529094
Methods	X-ray diffraction
Resolution	1.75 - 2.1 Å
Structure data	PDB-9mw1: Structure of SARM1 TIR domain bound to G8758 Method: X-RAY DIFFRACTION / Resolution: 2.1 Å PDB-9mw2: Structure of SARM1 TIR domain bound to G6831 Method: X-RAY DIFFRACTION / Resolution: 1.75 Å PDB-9mw3: Structure of SARM1 TIR domain bound to G2756 Method: X-RAY DIFFRACTION / Resolution: 1.93 Å
Chemicals	PDB-1bts: THE SOLUTION STRUCTURES OF THE FIRST AND SECOND TRANSMEMBRANE-SPANNING SEGMENTS OF BAND 3 ChemComp-HOH: WATER PDB-1bu7: CRYOGENIC STRUCTURE OF CYTOCHROME P450BM-3 HEME DOMAIN PDB-1btr: THE SOLUTION STRUCTURES OF THE FIRST AND SECOND TRANSMEMBRANE-SPANNING SEGMENTS OF BAND 3
Source	homo sapiens (human)
Keywords	LYASE / SARM1 / NADase