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Structure paper

TitleStructural Basis of the LARP4-Filamin A Interaction and Competition with Integrin beta 7 Tails.
Journal, issue, pagesJ. Mol. Biol., Vol. 437, Page 169262-169262, Year 2025
Publish dateFeb 17, 2025 (structure data deposition date)
AuthorsMao, Z. / Ding, Y. / Liu, Y. / Mei, K. / Nakamura, F.
External linksJ. Mol. Biol. / PubMed:40466905
MethodsX-ray diffraction
Resolution2.29 - 2.46 Å
Structure data

PDB-9lwx:
Crystal structure of the Filamin A repeat 21
Method: X-RAY DIFFRACTION / Resolution: 2.29 Å

PDB-9lxg:
Filamin A repeat 21 in complex with LARP4 Ala269-Asn281 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.46 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • esselenichthys carli (threeline prickleback)
KeywordsSIGNALING PROTEIN / Filamin / mechanotransduction / PROTEIN BINDING / FLNA / LARP4 / mechanosensing

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