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TitleImine Reductase-Catalyzed Remote Stereocontrol for Enantiodivergent Synthesis of Cyclohexylidene-Based Axially Chiral Amines.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 64, Page e202500572-e202500572, Year 2025
Publish dateOct 30, 2024 (structure data deposition date)
AuthorsLi, K. / Liu, Z. / Wang, B. / Huang, L. / Yu, L. / Zhou, Z. / Lin, L. / Fang, P. / Fu, H.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:40393926
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-9kbb:
3-hydroxyisobutyrate dehydrogenase
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-9kbc:
3-hydroxyisobutyrate dehydrogenase
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-HOH:
WATER

Source
  • micromonospora echinaurantiaca (bacteria)
KeywordsOXIDOREDUCTASE / oxidoreductase activity

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