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Structure paper

TitleInhibition of MIF with an Allosteric Inhibitor Triggers Cell Cycle Arrest in Acute Myeloid Leukemia.
Journal, issue, pagesAcs Omega, Vol. 10, Page 17441-17452, Year 2025
Publish dateApr 28, 2023 (structure data deposition date)
AuthorsPantouris, G. / Khurana, L. / Tilstam, P. / Benner, A. / Cho, T.Y. / Lelaidier, M. / Perree, M. / Rosenbaum, Z. / Leng, L. / Foss, F. ...Pantouris, G. / Khurana, L. / Tilstam, P. / Benner, A. / Cho, T.Y. / Lelaidier, M. / Perree, M. / Rosenbaum, Z. / Leng, L. / Foss, F. / Bhandari, V. / Verma, A. / Bucala, R. / Lolis, E.J.
External linksAcs Omega / PubMed:40352549
MethodsX-ray diffraction
Resolution1.63 Å
Structure data

PDB-8son:
Crystal structure of macrophage migration inhibitory factor in complex with N-[3-(Trifluoromethyl)phenyl]-3-(2-chloroanilino)-2-cyano-3-thioxopropanamide
Method: X-RAY DIFFRACTION / Resolution: 1.63 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION


ChemComp, No image

ChemComp-30Y:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE/ISOMERASE INHIBITOR / inhibitor / complex / ISOMERASE / ISOMERASE-ISOMERASE INHIBITOR complex

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