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Structure paper

TitleSnake venom protection by a cocktail of varespladib and broadly neutralizing human antibodies.
Journal, issue, pagesCell, Vol. 188, Page 3117-3134.e11, Year 2025
Publish dateNov 19, 2023 (structure data deposition date)
AuthorsGlanville, J. / Bellin, M. / Pletnev, S. / Zhang, B. / Andrade, J.C. / Kim, S. / Tsao, D. / Verardi, R. / Bedi, R. / Liao, S. ...Glanville, J. / Bellin, M. / Pletnev, S. / Zhang, B. / Andrade, J.C. / Kim, S. / Tsao, D. / Verardi, R. / Bedi, R. / Liao, S. / Newland, R. / Bayless, N.L. / Youssef, S. / Tully, E.S. / Bylund, T. / Hirou, H. / Liu, T. / Kwong, P.D.
External linksCell / PubMed:40318633
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-8v13:
Crystal structure of Black mamba toxin in complex with Centi-SNX-B03 antibody
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • dendraspis polylepis polylepis (black mamba)
KeywordsANTITOXIN/IMMUNE SYSTEM / antivenom / 3-finger toxin / short neurotoxin / antibody / ANTITOXIN-IMMUNE SYSTEM complex

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