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TitleThe mechanism of YAP/TAZ transactivation and dual targeting for cancer therapy.
Journal, issue, pagesNat Commun, Vol. 16, Page 3855-3855, Year 2025
Publish dateMay 3, 2023 (structure data deposition date)
AuthorsYu, M. / Wang, J. / Zhang, X. / Zhang, H. / Li, C. / Li, J. / Lin, J. / Zheng, J. / Huang, L. / Li, Y. / Sun, S.
External linksNat Commun / PubMed:40274828
MethodsNMR (solution)
Structure data

PDB-8j9a:
Solution structure of ABD3 (residues 453-561) of human MED15 isoform 2
Method: SOLUTION NMR

PDB-8wrg:
Solution structure of the TAD domain (450-504) of human transcriptional coactivator YAP1
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Mediator of RNA polymerase II transcription subunit 15 / transcriptional coactivator / transcription factor complex

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