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Structure paper

TitleA facultative plasminogen-independent thrombolytic enzyme from Sipunculus nudus.
Journal, issue, pagesNat Commun, Vol. 16, Page 3852-3852, Year 2025
Publish dateJun 12, 2024 (structure data deposition date)
AuthorsTang, M. / Ma, G. / Xu, C. / Yang, H. / Lin, H. / Bian, C. / Hu, C. / Lu, M. / Chen, L. / Jie, W. ...Tang, M. / Ma, G. / Xu, C. / Yang, H. / Lin, H. / Bian, C. / Hu, C. / Lu, M. / Chen, L. / Jie, W. / Yue, Z. / Jian, J. / Sun, Y. / Yan, H. / Zhou, J. / Zhang, X. / Liao, S. / Li, Z. / Cai, S. / Wu, Y. / Yang, K. / Xiong, Y. / Zhao, Y. / Lv, Z. / Xu, X. / Liu, C. / Xin, P. / Ye, L. / Cui, X. / Shi, Q. / Chen, X. / Xu, R.
External linksNat Commun / PubMed:40274794
MethodsX-ray diffraction
Resolution1.5 - 1.987 Å
Structure data

PDB-8zvs:
Crystal structure of snFPITE-n1
Method: X-RAY DIFFRACTION / Resolution: 1.987 Å

PDB-8zvx:
Crystal structure of snFPITE-n2
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-PMS:
phenylmethanesulfonic acid

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

Source
  • sipunculus nudus (marine worm)
KeywordsBLOOD CLOTTING / fibrin lysis / fibrinogen lysis / plasminogen activation / proteinase

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