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TitleChemically Induced Nuclear Pore Complex Protein Degradation via TRIM21.
Journal, issue, pagesAcs Chem. Biol., Vol. 20, Page 1020-1028, Year 2025
Publish dateJun 19, 2024 (structure data deposition date)
AuthorsLi, X. / Wang, Q. / Guo, A. / Qiu, Y. / Chen, Q. / Li, Y. / Zhang, L. / Guo, Y. / Meng, X. / Li, S. ...Li, X. / Wang, Q. / Guo, A. / Qiu, Y. / Chen, Q. / Li, Y. / Zhang, L. / Guo, Y. / Meng, X. / Li, S. / Liu, G. / Liu, J. / Cai, L. / Cheng, X. / Liu, C. / Wang, X. / Wood, A. / Murray, J. / Li, J. / Huang, X. / Dou, D.
External linksAcs Chem. Biol. / PubMed:40247740
MethodsX-ray diffraction
Resolution1.49 Å
Structure data

PDB-9ii5:
Crystal structure of human TRIM21 PRYSPRY in complex with compound 1
Method: X-RAY DIFFRACTION / Resolution: 1.49 Å

Chemicals

PDB-1d9f:
CRYSTAL STRUCTURE OF THE COMPLEX OF DNA POLYMERASE I KLENOW FRAGMENT WITH DNA TETRAMER CARRYING 2'-O-(3-AMINOPROPYL)-RNA MODIFICATION 5'-D(TT)-AP(U)-D(T)-3'

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE / complex / E3 ligase

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