EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Decoding the selective chemical modulation of CYP3A4.
ジャーナル・号・ページ	Nat Commun, Vol. 16, Page 3423-3423, Year 2025
掲載日	2024年5月20日 (構造データの登録日)
著者	Wang, J. / Nithianantham, S. / Chai, S.C. / Jung, Y.H. / Yang, L. / Ong, H.W. / Li, Y. / Zhang, Y. / Miller, D.J. / Chen, T.
リンク	Nat Commun / PubMed:40210880
手法	X線回折
解像度	2.25 - 3.4 Å
構造データ	PDB-9bv5: Crystal structure of human CYP3A4 in complex with SJ000362065 手法: X-RAY DIFFRACTION / 解像度: 2.71 Å PDB-9bv6: Crystal structure of human CYP3A4 in complex with SJ000388260 手法: X-RAY DIFFRACTION / 解像度: 3.1 Å PDB-9bv7: Crystal structure of human CYP3A4 in complex with SJ000310315 手法: X-RAY DIFFRACTION / 解像度: 3.21 Å PDB-9bv8: Crystal structure of human CYP3A4 in complex with SJYHJ-114 手法: X-RAY DIFFRACTION / 解像度: 3 Å PDB-9bv9: Crystal structure of human CYP3A4 in complex with Z56791366 手法: X-RAY DIFFRACTION / 解像度: 2.95 Å PDB-9bva: Crystal structure of human CYP3A4 in complex with SJYHJ-106 手法: X-RAY DIFFRACTION / 解像度: 3.02 Å PDB-9bvb: Crystal structure of human CYP3A4 in complex with SJYHJ-075 手法: X-RAY DIFFRACTION / 解像度: 3 Å PDB-9bvc: Crystal structure of human CYP3A4 in complex with SJYHJ-110 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-9ms1: Crystal structure of human CYP3A4 in complex with SJYHJ-111 手法: X-RAY DIFFRACTION / 解像度: 3.4 Å PDB-9ms2: Crystal structure of human CYP3A5 in complex with SJYHJ-111 手法: X-RAY DIFFRACTION / 解像度: 2.25 Å
化合物	ChemComp-HEM: PROTOPORPHYRIN IX CONTAINING FE PDB-1asv: Avian sarcoma virus integrase catalytic core domain ChemComp-EDO: 1,2-ETHANEDIOL / エチレングリコ-ル ChemComp-HOH: WATER PDB-1asu: AVIAN SARCOMA VIRUS INTEGRASE CATALYTIC CORE DOMAIN CRYSTALLIZED FROM 2% PEG 400, 2M AMMONIUM SULFATE, HEPES PH 7.5 ChemComp-PG0: 2-(2-METHOXYETHOXY)ETHANOL / ジエチレングリコ-ルモノメチルエ-テル / 阻害剤, 沈殿剤YM PDB-1ast: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES PDB-1ass: APICAL DOMAIN OF THE CHAPERONIN FROM THERMOPLASMA ACIDOPHILUM PDB-1asr: Unknown entry PDB-1asq: X-RAY STRUCTURES AND MECHANISTIC IMPLICATIONS OF THREE FUNCTIONAL DERIVATIVES OF ASCORBATE OXIDASE FROM ZUCCHINI: REDUCED-, PEROXIDE-, AND AZIDE-FORMS PDB-1asp: X-RAY STRUCTURES AND MECHANISTIC IMPLICATIONS OF THREE FUNCTIONAL DERIVATIVES OF ASCORBATE OXIDASE FROM ZUCCHINI: REDUCED-, PEROXIDE-, AND AZIDE-FORMS PDB-1aso: X-RAY STRUCTURES AND MECHANISTIC IMPLICATIONS OF THREE FUNCTIONAL DERIVATIVES OF ASCORBATE OXIDASE FROM ZUCCHINI: REDUCED-, PEROXIDE-, AND AZIDE-FORMS PDB-1bnx: STRUCTURAL STUDIES ON THE EFFECTS OF THE DELETION IN THE RED CELL ANION EXCHANGER (BAND3, AE1) ASSOCIATED WITH SOUTH EAST ASIAN OVALOCYTOSIS. ChemComp-PEG: DI(HYDROXYETHYL)ETHER / ジエチレングリコ-ル ChemComp-SO4*: SULFATE ION / 硫酸ジアニオン
由来	homo sapiens (ヒト)
キーワード	OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / Cytochrome P450 3A4 / CYP3A4 / CYP3A4-selective inhibitor / drug metabolizing enzyme / OXIDOREDUCTASE / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex / OXIDOREDUCTASE/INHIBITOR / OXIDOREDUCTASE-INHIBITOR complex / Cytochrome P450 3A5 / CYP3A5 / CYP3A5-selective inhibitor