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TitleO -Cyanobenzaldehydes Irreversibly Modify Both Buried and Exposed Lysine Residues in Live Cells.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 147, Page 11955-11963, Year 2025
Publish dateNov 29, 2024 (structure data deposition date)
AuthorsLing, H. / Li, L. / Duan, L. / Huang, W. / Zheng, J. / Zhang, S. / Li, X. / Qiu, X. / Zhou, Y. / Ma, N. ...Ling, H. / Li, L. / Duan, L. / Huang, W. / Zheng, J. / Zhang, S. / Li, X. / Qiu, X. / Zhou, Y. / Ma, N. / Ren, X. / Zhang, J. / Wang, Z. / Zhao, Y. / Tian, R. / Zhang, Z.M. / Ding, K.
External linksJ. Am. Chem. Soc. / PubMed:40150802
MethodsX-ray diffraction
Resolution2.2 - 2.75 Å
Structure data

PDB-9ks5:
The crystal structure of ABL1 in complex with K-CNBA-1
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-9ks6:
The crystal structure of AURKA in complex with K-CNBA-1
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsUNKNOWN FUNCTION / ABL1 / K-CBA-1 / LYSINE MODIFICATION / IRREVERSIBLE COVALENT PROBE / AURKA / K-CNBA-1

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