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TitleEngineering oxypurinol-responsive riboswitches based on bacterial xanthine aptamers for gene expression control in mammalian cell culture.
Journal, issue, pagesNucleic Acids Res., Vol. 53, Year 2025
Publish dateAug 14, 2023 (structure data deposition date)
AuthorsHedwig, V. / Sporing, M. / Ottlinger, J. / Kose, S. / Nar, H. / Schnapp, G. / Gottschling, D. / Klein, H. / Aspnes, G. / Klugmann, M. / Hartig, J.S.
External linksNucleic Acids Res. / PubMed:40087885
MethodsX-ray diffraction
Resolution2.63 Å
Structure data

PDB-8q6n:
Xanthin riboswitch in complex with oxypurinol
Method: X-RAY DIFFRACTION / Resolution: 2.63 Å

Chemicals

ChemComp-141:
Oxypurinol / inhibitor*YM

ChemComp-HOH:
WATER

Source
  • ideonella sp. b508-1 (bacteria)
KeywordsRNA / RNA riboswitch xanthin ligand

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