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Structure paper

TitleIdentification of a ligand-binding site on tubulin mediating the tubulin-RB3 interaction.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 122, Page e2424098122-e2424098122, Year 2025
Publish dateJul 2, 2024 (structure data deposition date)
AuthorsLi, Y. / Zhang, C. / Tang, D. / Wang, T. / Yan, W. / Yang, L. / Bai, P. / Tang, M. / Pei, H. / Chen, L. ...Li, Y. / Zhang, C. / Tang, D. / Wang, T. / Yan, W. / Yang, L. / Bai, P. / Tang, M. / Pei, H. / Chen, L. / Chen, Q. / Yang, J.
External linksProc. Natl. Acad. Sci. USA / PubMed:40067895
MethodsX-ray diffraction
Resolution2.75 - 2.86 Å
Structure data

PDB-9im5:
Tubulin-RB3(MUT)-TTL-Y12
Method: X-RAY DIFFRACTION / Resolution: 2.86 Å

PDB-9imo:
Crystal structure of Tubulin-RB3-TTL-Y12
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

PDB-1l2t:
Dimeric Structure of MJ0796, a Bacterial ABC Transporter Cassette

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-ACP:
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER / AMP-PCP, energy-carrying molecule analogue*YM

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
  • gallus gallus (chicken)
  • sus scrofa (pig)
KeywordsCELL CYCLE / Tubulin

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