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Structure paper

TitleA monomer-dimer switch modulates the activity of plant adenosine kinase.
Journal, issue, pagesJ. Exp. Bot., Vol. 76, Page 3457-3479, Year 2025
Publish dateDec 12, 2023 (structure data deposition date)
AuthorsKopecny, D.J. / Vigouroux, A. / Belicek, J. / Kopecna, M. / Koncitikova, R. / Friedecka, J. / Mik, V. / Supikova, K. / Humplik, J.F. / Le Berre, M. ...Kopecny, D.J. / Vigouroux, A. / Belicek, J. / Kopecna, M. / Koncitikova, R. / Friedecka, J. / Mik, V. / Supikova, K. / Humplik, J.F. / Le Berre, M. / Plancqueel, S. / Strnad, M. / von Schwartzenberg, K. / Novak, O. / Morera, S. / Kopecny, D.
External linksJ. Exp. Bot. / PubMed:40063605
MethodsX-ray diffraction
Resolution1.73 - 2.359 Å
Structure data

PDB-8rf7:
Crystal structure of maize adenosine kinase 2 (ADK2) apoform
Method: X-RAY DIFFRACTION / Resolution: 2.051 Å

PDB-8rgj:
Structure of maize adenosine kinase 2 (ADK2) in complex with AMP-PCP
Method: X-RAY DIFFRACTION / Resolution: 2.359 Å

PDB-8rpa:
Crystal structure of Zea mays adenosine kinase 3 (ZmADK3) in complex with AP5A
Method: X-RAY DIFFRACTION / Resolution: 2.261 Å

PDB-9fw6:
A ternary complex of plant adenosine kinase 1 from moss Physcomitrella patens (PpADK1) with adenosine and ADP
Method: X-RAY DIFFRACTION / Resolution: 1.73 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-ACT:
ACETATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-ACP:
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER / AMP-PCP, energy-carrying molecule analogue*YM

ChemComp-AP5:
BIS(ADENOSINE)-5'-PENTAPHOSPHATE

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-CL:
Unknown entry

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-ADN:
ADENOSINE

ChemComp-NA:
Unknown entry

Source
  • zea mays (maize)
  • physcomitrium patens (plant)
KeywordsTRANSFERASE / Adenosine kinase / ATP / adenosine / cytokinin / ternary complex / inhibitor / Plant enzyme / kinase / complex / PLANT PROTEIN

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