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TitleCrystal structure of the S-adenosylmethionine-dependent mycolic acid synthase UmaA from Mycobacterium tuberculosis.
Journal, issue, pagesActa Crystallogr. ,Sect. F, Vol. 81, Page 146-154, Year 2025
Publish dateMar 3, 2021 (structure data deposition date)
AuthorsTeng, S. / Wang, J. / Sroge, C.D. / Abendroth, J. / Lorimer, D.D. / Horanyi, P.S. / Edwards, T.E. / Tillery, L. / Craig, J.K. / Van Voorhis, W.C. ...Teng, S. / Wang, J. / Sroge, C.D. / Abendroth, J. / Lorimer, D.D. / Horanyi, P.S. / Edwards, T.E. / Tillery, L. / Craig, J.K. / Van Voorhis, W.C. / Myler, P.J. / Smith, C.L.
External linksActa Crystallogr. ,Sect. F / PubMed:40059638
MethodsX-ray diffraction
Resolution1.95 Å
Structure data

PDB-7lxi:
Crystal structure of S-adenosylmethionine-dependent methyltransferase UmaA from Mycobacterium tuberculosis in complex with SAH
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-P6G:
HEXAETHYLENE GLYCOL / precipitant*YM

ChemComp-NO3:
NITRATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PO4:
PHOSPHATE ION

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsTRANSFERASE / SSGCID / S-adenosylmethionine-dependent methyltransferase / SAM-dependent methyltransferase / UmaA / Mycobacterium tuberculosis / short-chain fatty acid modification / SAH / S-Adenosyl-l-homocysteine / Structural Genomics / Seattle Structural Genomics Center for Infectious Disease

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