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Structure paper

TitleA family of bacterial Josephin-like deubiquitinases with an irreversible cleavage mode.
Journal, issue, pagesMol. Cell, Vol. 85, Page 1202-1215.e5, Year 2025
Publish dateApr 30, 2024 (structure data deposition date)
AuthorsHermanns, T. / Kolek, S. / Uthoff, M. / de Heiden, R.A. / Mulder, M.P.C. / Baumann, U. / Hofmann, K.
External linksMol. Cell / PubMed:40037356
MethodsX-ray diffraction
Resolution1.89 - 2.56 Å
Structure data

PDB-9f5t:
Ubiquitin C-terminal clippase BpJOS
Method: X-RAY DIFFRACTION / Resolution: 2.56 Å

PDB-9fn4:
DUBS Parachlamydia sp. PcJOS
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-9fpa:
DUBS Parachlamydia sp. PcJOS orthorhombic crystal form
Method: X-RAY DIFFRACTION / Resolution: 2.18 Å

PDB-9g7g:
Structure of the clippase PaJOS from Pigmentiphaga aceris
Method: X-RAY DIFFRACTION / Resolution: 1.89 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-TLA:
L(+)-TARTARIC ACID

ChemComp-CIT:
CITRIC ACID

ChemComp-AYE:
prop-2-en-1-amine

Source
  • burkholderia pyrrocinia (bacteria)
  • homo sapiens (human)
  • parachlamydia sp. (bacteria)
  • pigmentiphaga aceris (bacteria)
KeywordsHYDROLASE / Deubiquitinase / Ubiquitin C-terminal clippase / Debiquitinylating enzyme / Ubiquitin / Clippase

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