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TitleDisrupting the network of co-evolving amino terminal domain residues relieves mitochondrial calcium uptake inhibition by MCUb.
Journal, issue, pagesComput Struct Biotechnol J, Vol. 27, Page 190-213, Year 2025
Publish dateOct 25, 2023 (structure data deposition date)
AuthorsColussi, D.M. / Grainger, R. / Noble, M. / Lake, T. / Junop, M. / Stathopulos, P.B.
External linksComput Struct Biotechnol J / PubMed:40017731
MethodsX-ray diffraction
Resolution1.63 Å
Structure data

PDB-8urg:
Human mitochondrial calcium uniporter crystal structure (residues 74-165 resolved) with lithium
Method: X-RAY DIFFRACTION / Resolution: 1.63 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsMETAL TRANSPORT / Beta-grasp fold

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