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| Title | Optimal Stapling of a Helical Peptide-Foldamer Hybrid Using a C-Terminal 4-Mercaptoproline Enhances Protein Surface Recognition and Cellular Activity. |
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| Journal, issue, pages | Chemistry, Vol. 31, Page e202403330-e202403330, Year 2025 |
| Publish date | Jun 17, 2024 (structure data deposition date) |
Authors | Neuville, M. / Bourgeais, M. / Buratto, J. / Saragaglia, C. / Li, B. / Galeano-Otero, I. / Mauran, L. / Varajao, L. / Goudreau, S.R. / Kauffmann, B. ...Neuville, M. / Bourgeais, M. / Buratto, J. / Saragaglia, C. / Li, B. / Galeano-Otero, I. / Mauran, L. / Varajao, L. / Goudreau, S.R. / Kauffmann, B. / Thinon, E. / Pasco, M. / Khatib, A.M. / Guichard, G. |
External links | Chemistry / PubMed:40014761 |
| Methods | X-ray diffraction |
| Resolution | 1.841 - 2 Å |
| Structure data | ![]() PDB-9fql: ![]() PDB-9gfk: |
| Chemicals | ![]() ChemComp-PO4: ![]() ChemComp-HOH: ![]() ChemComp-SO4: |
| Source |
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Keywords | ANTITUMOR PROTEIN / PROTEIN FOLDAMER COMPLEX / PROTEIN FOLDAMER INTERACTIONS / PROTEIN PROTEIN INTERACTION INHIBITOR / UREA BASED CHIMERA FOLDAMER / LIGASE / HDM2 / staple peptide / helical Peptide-foldamer |
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homo sapiens (human)
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