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| Title | LOPAC library screening identifies suramin as a TRIM21 binder with a unique binding mode revealed by crystal structure. |
|---|---|
| Journal, issue, pages | Acta Crystallogr. ,Sect. F, Vol. 81, Page 101-107, Year 2025 |
| Publish date | Sep 17, 2024 (structure data deposition date) |
Authors | Kim, Y. / Knapp, S. / Kramer, A. |
External links | Acta Crystallogr. ,Sect. F / PubMed:39955622 |
| Methods | X-ray diffraction |
| Resolution | 1.3 Å |
| Structure data | ![]() PDB-9gte: |
| Chemicals | ![]() ChemComp-EDO: ![]() ChemComp-SVR: ![]() ChemComp-HOH: |
| Source |
|
Keywords | LIGASE / TRIM21 / PRY-SPRY domain / Suramin / E3 Ligase |
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