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TitleA Stereoselective Decarboxylative Aromatase/Cyclase Directs the Biosynthesis of an Axially Chiral Biphenyl Framework in Fasamycin.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 147, Page 5596-5601, Year 2025
Publish dateFeb 4, 2025 (structure data deposition date)
AuthorsJiang, K. / Zhu, C. / Yan, X. / Li, G. / Lin, Z. / Deng, Z. / Luo, S. / Qu, X.
External linksJ. Am. Chem. Soc. / PubMed:39910892
MethodsX-ray diffraction
Resolution2.01 Å
Structure data

PDB-9lsd:
Crystal structure of a polyketide cyclase FasU from Streptomyces kanamyceticus
Method: X-RAY DIFFRACTION / Resolution: 2.01 Å

Chemicals

ChemComp-AE3:
2-(2-ETHOXYETHOXY)ETHANOL

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • streptomyces kanamyceticus (bacteria)
KeywordsBIOSYNTHETIC PROTEIN / polyketide / cyclase

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