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TitleAntibody-secreting cell repertoires hold high-affinity anti-rocuronium specificities that can induce anaphylaxis in vivo.
Journal, issue, pagesJ. Allergy Clin. Immunol., Vol. 155, Page 1557-1574, Year 2025
Publish dateJul 19, 2024 (structure data deposition date)
AuthorsDejoux, A. / Zhu, Q. / Woolfe, A. / Godon, O. / Ellouze, S. / Mottet, G. / Castrillon, C. / Gillis, C. / Pecalvel, C. / Ganneau, C. ...Dejoux, A. / Zhu, Q. / Woolfe, A. / Godon, O. / Ellouze, S. / Mottet, G. / Castrillon, C. / Gillis, C. / Pecalvel, C. / Ganneau, C. / Iannascoli, B. / Lemoine, F. / Saul, F. / England, P. / Reber, L.L. / Gouel-Cheron, A. / de Chaisemartin, L. / Haouz, A. / Millot, G.A. / Bay, S. / Gerard, A. / Jonsson, F. / Chollet-Martin, S. / Bruhns, P.
External linksJ. Allergy Clin. Immunol. / PubMed:39892658
MethodsX-ray diffraction
Resolution1.2 - 2.373 Å
Structure data

PDB-9g6q:
scFv IP11 in complex with rocuronium
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

PDB-9g6r:
Fab-IP8 in complex with rocuronium
Method: X-RAY DIFFRACTION / Resolution: 1.72 Å

PDB-9g6s:
Fab-IP2 in complex with rocuronium
Method: X-RAY DIFFRACTION / Resolution: 2.373 Å

Chemicals

ChemComp-RBR:
rocuronium

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / immunotherapy / anaphylaxis / Fab

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