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Structure paper

TitleCrystal structure of MutYX: A novel clusterless adenine DNA glycosylase with a distinct C-terminal domain and 8-Oxoguanine recognition sphere.
Journal, issue, pagesBiorxiv, Year 2025
Publish dateNov 1, 2023 (structure data deposition date)
AuthorsTrasvina-Arenas, C.H. / Hashemian, M. / Malek, M. / Merrill, S. / Fisher, A.J. / David, S.S.
External linksBiorxiv / PubMed:39803464
MethodsX-ray diffraction
Resolution1.55 Å
Structure data

PDB-8uuc:
Crystal structure of a bacterial clusterless MutYX bound to an Abasic site analog (THF) opposite d(8-oxo-G)
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • eggerthella sp. yy7918 (bacteria)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN/DNA / DNA glycosylase / Base Excision Repair / DNA-protein complex / DNA repair / DNA BINDING PROTEIN / DNA BINDING PROTEIN-DNA complex

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