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TitleBiophysical and biochemical evidence for the role of acetate kinases (AckAs) in an acetogenic pathway in pathogenic spirochetes.
Journal, issue, pagesPlos One, Vol. 20, Page e0312642-e0312642, Year 2025
Publish dateOct 5, 2024 (structure data deposition date)
AuthorsDeka, R.K. / Tso, S.C. / Liu, W.Z. / Brautigam, C.A.
External linksPlos One / PubMed:39787173
MethodsX-ray diffraction
Resolution1.3 - 1.36 Å
Structure data

PDB-9dv8:
The Apo structure of AckA from Treponema vincentii
Method: X-RAY DIFFRACTION / Resolution: 1.36 Å

PDB-9dv9:
The AMP-bound structure of AckA from Treponema vincentii
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-AMP:
ADENOSINE MONOPHOSPHATE / AMP*YM

ChemComp-SO4:
SULFATE ION

Source
  • treponema vincentii (bacteria)
  • treponema pallidum (bacteria)
KeywordsTRANSFERASE / Acetate kinase / oral pathogen / AMP

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