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TitleHeat-sterilizable antibody mimics designed on the cold shock protein scaffold from hyperthermophile Thermotoga maritima.
Journal, issue, pagesProtein Sci., Vol. 34, Page e70018-e70018, Year 2025
Publish dateOct 7, 2024 (structure data deposition date)
AuthorsAmesaka, H. / Tachibana, M. / Hara, M. / Toya, S. / Nakagawa, H. / Matsumura, H. / Hirata, A. / Fujihashi, M. / Takano, K. / Tanaka, S.I.
External linksProtein Sci. / PubMed:39724358
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-9ju4:
Crystal structure of the Thermotoga maritima cold shock protein mutant Est#13 in complex with AacEst
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-PMS:
phenylmethanesulfonic acid

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • alicyclobacillus acidocaldarius (bacteria)
  • thermotoga maritima (bacteria)
KeywordsPROTEIN BINDING / Antibody-mimics / Cold shock protein / Refolding / Heat sterilization / Freeze-drying

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