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TitleDiscovery of a non-nucleotide stimulator of interferon genes (STING) agonist with systemic antitumor effect.
Journal, issue, pagesMedComm (2020), Vol. 6, Page e70001-e70001, Year 2025
Publish dateJun 25, 2024 (structure data deposition date)
AuthorsWang, X. / Zhan, Z. / Wang, Z. / Zhang, Y. / Zhao, K. / Li, H. / Zhou, X. / Guo, Y. / Fan, F. / Ding, J. ...Wang, X. / Zhan, Z. / Wang, Z. / Zhang, Y. / Zhao, K. / Li, H. / Zhou, X. / Guo, Y. / Fan, F. / Ding, J. / Geng, M. / Yu, X. / Duan, W. / Xie, Z.
External linksMedComm (2020) / PubMed:39712456
MethodsX-ray diffraction
Resolution1.81 Å
Structure data

PDB-9ijn:
STING LBD domain with an agonist DW18343
Method: X-RAY DIFFRACTION / Resolution: 1.81 Å

Chemicals

PDB-1d9i:
STRUCTURE OF THROMBIN COMPLEXED WITH SELECTIVE NON-ELECTOPHILIC INHIBITORS HAVING CYCLOHEXYL MOIETIES AT P1

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / STING LBD domain / Agonist

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