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| Title | A bacterial methyltransferase that initiates biotin synthesis, an attractive anti-ESKAPE druggable pathway. |
|---|---|
| Journal, issue, pages | Sci Adv, Vol. 10, Page eadp3954-eadp3954, Year 2024 |
| Publish date | Nov 27, 2023 (structure data deposition date) |
Authors | Su, Z. / Zhang, W. / Shi, Y. / Cui, T. / Xu, Y. / Yang, R. / Huang, M. / Zhou, C. / Zhang, H. / Lu, T. ...Su, Z. / Zhang, W. / Shi, Y. / Cui, T. / Xu, Y. / Yang, R. / Huang, M. / Zhou, C. / Zhang, H. / Lu, T. / Qu, J. / He, Z.G. / Gan, J. / Feng, Y. |
External links | Sci Adv / PubMed:39705367 |
| Methods | X-ray diffraction |
| Resolution | 1.72 - 2.54 Å |
| Structure data | ![]() PDB-8x8i: ![]() PDB-8x8j: |
| Chemicals | ![]() ChemComp-SAM: ![]() ChemComp-HOH: ![]() ChemComp-SFG: ![]() ChemComp-GOL: ![]() ChemComp-SO4: ![]() ChemComp-DIO: |
| Source |
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Keywords | TRANSFERASE / BioC methyltransferase / Druggable pathway / Biotin synthesis |
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acinetobacter baumannii (bacteria)
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