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TitleDevelopment of a Highly Selective NanoBRET Probe to Assess MAGL Inhibition in Live Cells.
Journal, issue, pagesChembiochem, Vol. 26, Page e202400704-e202400704, Year 2025
Publish dateJul 2, 2024 (structure data deposition date)
AuthorsGazzi, T. / Brennecke, B. / Olikauskas, V. / Hochstrasser, R. / Wang, H. / Keen Chao, S. / Atz, K. / Mostinski, Y. / Topp, A. / Heer, D. ...Gazzi, T. / Brennecke, B. / Olikauskas, V. / Hochstrasser, R. / Wang, H. / Keen Chao, S. / Atz, K. / Mostinski, Y. / Topp, A. / Heer, D. / Kaufmann, I. / Ritter, M. / Gobbi, L. / Hornsperger, B. / Wagner, B. / Richter, H. / O'Hara, F. / Wittwer, M.B. / Jul Hansen, D. / Collin, L. / Kuhn, B. / Benz, J. / Grether, U. / Nazare, M.
External linksChembiochem / PubMed:39607084
MethodsX-ray diffraction
Resolution1.43 Å
Structure data

PDB-9fy5:
CRYSTAL STRUCTURE OF HUMAN MONOACYLGLYCEROL LIPASE WITH COMPOUND
Method: X-RAY DIFFRACTION / Resolution: 1.43 Å

Chemicals

PDB-1ig3:
Mouse Thiamin Pyrophosphokinase Complexed with Thiamin

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Alpha/Beta Hydrolase / Serine Esterase

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