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TitleBiophysical characterization of blood coagulation factor VIII binding to lipid nanodiscs that mimic activated platelet surfaces.
Journal, issue, pagesJ. Thromb. Haemost., Year 2024
Publish dateAug 13, 2024 (structure data deposition date)
AuthorsAvery, N.G. / Young, I.R. / Lu, S. / Vaughan, J.D. / Korus, P.S. / Richardson, T.N. / Childers, K.C. / Smirnov, S.L. / Spiegel Jr., P.C.
External linksJ. Thromb. Haemost. / PubMed:39549835
MethodsX-ray diffraction
Resolution1.83 Å
Structure data

PDB-9d5d:
Crystal Structure of Blood Coagulation Factor VIII C2 Domain Mutant L2251A/L2252A
Method: X-RAY DIFFRACTION / Resolution: 1.83 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsBLOOD CLOTTING / Blood coagulation factor VIII / lipid binding protein / factor VIII C2 domain mutant

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