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Structure paper

TitleStructure and genome editing activity of the novel CRISPR-Cas12o1 effector.
Journal, issue, pagesCell Res, Vol. 35, Issue 2, Page 145-148, Year 2025
Publish dateNov 8, 2024
AuthorsZhiqiang Duan / Xi Zhang / Jun-Tao Zhang / Xingkun Ji / Ruiheng Liu / Ying Chen / Shanshan Li / Nannan Jia / Huizhi Gao / Yu Xin / Ning Jia / Jian-Kang Zhu /
External linksCell Res / PubMed:39516663 / PubMed Central
MethodsEM (single particle)
Resolution3.1 - 3.2 Å
Structure data

EMDB-35588: Cryo-EM structure of Cas12o1-crRNA-DNA complex at 3.1 Angstroms resolution, Conformation 1
Method: EM (single particle) / Resolution: 3.1 Å

EMDB-35590: Cryo-EM structure of Cas12o1-crRNA-DNA complex at 3.1 Angstroms resolution, Conformation 2
Method: EM (single particle) / Resolution: 3.1 Å

38238

8xca

EMDB-38238, PDB-8xca:
Cryo-EM structure of Cas12o1, crRNA and target DNA complex
Method: EM (single particle) / Resolution: 3.1 Å

38239

8xcc

EMDB-38239, PDB-8xcc:
Cryo-EM structure of Cas12o1 (E100K), crRNA and target DNA complex
Method: EM (single particle) / Resolution: 3.2 Å

Source
  • unidentified (others)
  • unclassified sequences (unknown)
KeywordsRNA BINDING PROTEIN/RNA/DNA / Crispr-Cas protein / RNA BINDING PROTEIN-RNA-DNA COMPLEX

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