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TitleStructural basis of the C-terminal domain of SARS-CoV-2 N protein in complex with GMP reveals critical residues for RNA interaction.
Journal, issue, pagesBioorg. Med. Chem. Lett., Page 130014-130014, Year 2024
Publish dateMay 30, 2022 (structure data deposition date)
AuthorsNi, X. / Han, Y. / Yu, J. / Zhou, R. / Lei, J.
External linksBioorg. Med. Chem. Lett. / PubMed:39489230
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-7xxk:
Crystal structure of SARS-CoV-2 N-CTD in complex with GMP
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-SCN:
THIOCYANATE ION

ChemComp-5GP:
GUANOSINE-5'-MONOPHOSPHATE

ChemComp-K:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-GUN:
GUANINE

ChemComp-NA:
Unknown entry

ChemComp-GMP:
GUANOSINE

ChemComp-HOH:
WATER

Source
  • severe acute respiratory syndrome coronavirus 2
KeywordsVIRAL PROTEIN / Coronavirus / C-terminal domain / nucleocapsid / GMP

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