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TitleRational mutagenesis of an epoxide hydrolase and its structural mechanism for the enantioselectivity improvement toward chiral ortho-fluorostyrene oxide.
Journal, issue, pagesInt. J. Biol. Macromol., Vol. 282, Page 136864-136864, Year 2024
Publish dateDec 20, 2023 (structure data deposition date)
AuthorsLu, Z.Y. / Liao, X. / Jing, W.W. / Liu, K.K. / Ren, Q.G. / He, Y.C. / Hu, D.
External linksInt. J. Biol. Macromol. / PubMed:39476898
MethodsX-ray diffraction
Resolution2.175 Å
Structure data

PDB-8xiz:
Crystal structure of an epoxide hydrolase mutant A250IC/L344V from Aspergillus usamii E001 at 2.17 Angstroms resolution
Method: X-RAY DIFFRACTION / Resolution: 2.175 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • aspergillus usamii (mold)
KeywordsHYDROLASE / Alpha and beta proteins / alpha/beta-Hydrolases / Styrene Oxide / Epoxide Hydrolase

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