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TitleAn archaic HLA class I receptor allele diversifies natural killer cell-driven immunity in First Nations peoples of Oceania.
Journal, issue, pagesCell, Vol. 187, Page 7008-, Year 2024
Publish dateApr 29, 2024 (structure data deposition date)
AuthorsLoh, L. / Saunders, P.M. / Faoro, C. / Font-Porterias, N. / Nemat-Gorgani, N. / Harrison, G.F. / Sadeeq, S. / Hensen, L. / Wong, S.C. / Widjaja, J. ...Loh, L. / Saunders, P.M. / Faoro, C. / Font-Porterias, N. / Nemat-Gorgani, N. / Harrison, G.F. / Sadeeq, S. / Hensen, L. / Wong, S.C. / Widjaja, J. / Clemens, E.B. / Zhu, S. / Kichula, K.M. / Tao, S. / Zhu, F. / Montero-Martin, G. / Fernandez-Vina, M. / Guethlein, L.A. / Vivian, J.P. / Davies, J. / Mentzer, A.J. / Oppenheimer, S.J. / Pomat, W. / Ioannidis, A.G. / Barberena-Jonas, C. / Moreno-Estrada, A. / Miller, A. / Parham, P. / Rossjohn, J. / Tong, S.Y.C. / Kedzierska, K. / Brooks, A.G. / Norman, P.J.
External linksCell / PubMed:39476840
MethodsX-ray diffraction
Resolution1.75 - 3 Å
Structure data

PDB-9bl2:
KIR3DL1*001 in complex with HLA-B*57:03 presenting the AW10 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-9bl3:
KIR3DL1*114 in complex with HLA-B*57:03 presenting the AW10 peptide
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-9bl4:
KIR3DL1*086 in complex with HLA-B*57:03 presenting the AW10 peptide
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-9bl5:
KIR3DL1*001 in complex with HLA-A*24:02 presenting the TW9 peptide
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-9bl6:
KIR3DL1*114 in complex with HLA-A*24:02 presenting the TW9 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-9bl9:
KIR3DL1*114 in complex with HLA-A*24:02 presenting the NEF peptide
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-9bla:
KIR3DL1*086 in complex with HLA-A*24:02 presenting the NEF peptide
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • influenza a virus
  • human immunodeficiency virus
  • human immunodeficiency virus 1
KeywordsIMMUNE SYSTEM / immunoglobulin fold / natural killer cell receptor / Kir

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