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TitleA novel N 4, N 4-dimethylcytidine in the archaeal ribosome enhances hyperthermophily.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 121, Page e2405999121-e2405999121, Year 2024
Publish dateFeb 8, 2024 (structure data deposition date)
AuthorsFluke, K.A. / Dai, N. / Wolf, E.J. / Fuchs, R.T. / Ho, P.S. / Talbott, V. / Elkins, L. / Tsai, Y.L. / Schiltz, J. / Febvre, H.P. ...Fluke, K.A. / Dai, N. / Wolf, E.J. / Fuchs, R.T. / Ho, P.S. / Talbott, V. / Elkins, L. / Tsai, Y.L. / Schiltz, J. / Febvre, H.P. / Czarny, R. / Robb, G.B. / Correa Jr., I.R. / Santangelo, T.J.
External linksProc. Natl. Acad. Sci. USA / PubMed:39471227
MethodsX-ray diffraction
Resolution1.95 Å
Structure data

PDB-8vyd:
A novel synthase generates m4(2)C to stabilize the archaeal ribosome
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • thermococcus kodakarensis (archaea)
KeywordsRNA BINDING PROTEIN / N4 / N4-dimethylcytidine / synthase / RNA modifications / hyperthermophile

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