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Structure paper

TitleMolecular basis for the transcriptional regulation of an epoxide-based virulence circuit in Pseudomonas aeruginosa.
Journal, issue, pagesNucleic Acids Res., Year 2024
Publish dateJan 25, 2019 (structure data deposition date)
AuthorsHe, S. / Taher, N.M. / Simard, A.R. / Hvorecny, K.L. / Ragusa, M.J. / Bahl, C.D. / Hickman, A.B. / Dyda, F. / Madden, D.R.
External linksNucleic Acids Res. / PubMed:39413156
MethodsX-ray diffraction
Resolution2.6 - 3 Å
Structure data

PDB-6nsm:
TetR family transcriptional regulator CifR C99T-C107S-C181R Cysteines mutant complexed with 26bp double-strand operator DNA
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-6nsn:
TetR family transcriptional regulator CifR C99T-C181R Cysteines mutant complexed with 26bp double-strand operator DNA
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-6nsr:
TetR family transcriptional regulator CifR C99T-C181R cysteine mutant complexed with 26bp double-strand operator DNA and apo-CifR C99T-C181R
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • pseudomonas aeruginosa ucbpp-pa14 (bacteria)
  • pseudomonas aeruginosa (bacteria)
KeywordsTRANSCRIPTION/DNA / repressor / DNA-binding complex / epoxide sensing protein / TRANSCRIPTION-DNA complex / Epoxide sensing / protein-DNA complex

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