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Structure paper

Titlealpha-Amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase catalyzes enol/keto tautomerization of oxaloacetate.
Journal, issue, pagesJ. Biol. Chem., Vol. 300, Page 107878-107878, Year 2024
Publish dateMar 24, 2024 (structure data deposition date)
AuthorsYang, Y. / Davis, I. / Altman, R.A. / Liu, A.
External linksJ. Biol. Chem. / PubMed:39395800
MethodsX-ray diffraction
Resolution2.02 - 2.22 Å
Structure data

PDB-8yt1:
Crystal structure of ACMSD in complex with malonate
Method: X-RAY DIFFRACTION / Resolution: 2.22 Å

PDB-8yt2:
Crystal structure of ACMSD mutant W194A
Method: X-RAY DIFFRACTION / Resolution: 2.02 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MLA:
MALONIC ACID

ChemComp-HOH:
WATER

Source
  • pseudomonas fluorescens (bacteria)
KeywordsLYASE / kynurenine / decarboxylase / NAD homeostasis / tryptophan metabolism / metalloenzyme

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