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| Title | Ziftomenib in relapsed or refractory acute myeloid leukaemia (KOMET-001): a multicentre, open-label, multi-cohort, phase 1 trial. |
|---|---|
| Journal, issue, pages | Lancet Oncol, Vol. 25, Page 1310-1324, Year 2024 |
| Publish date | Dec 11, 2023 (structure data deposition date) |
 Authors | Wang, E.S. / Issa, G.C. / Erba, H.P. / Altman, J.K. / Montesinos, P. / DeBotton, S. / Walter, R.B. / Pettit, K. / Savona, M.R. / Shah, M.V. ...Wang, E.S. / Issa, G.C. / Erba, H.P. / Altman, J.K. / Montesinos, P. / DeBotton, S. / Walter, R.B. / Pettit, K. / Savona, M.R. / Shah, M.V. / Kremyanskaya, M. / Baer, M.R. / Foran, J.M. / Schiller, G. / Ades, L. / Heiblig, M. / Berthon, C. / Peterlin, P. / Rodriguez-Arboli, E. / Salamero, O. / Patnaik, M.M. / Papayannidis, C. / Grembecka, J. / Cierpicki, T. / Clegg, B. / Ray, J. / Linhares, B.M. / Nie, K. / Mitra, A. / Ahsan, J.M. / Tabachri, M. / Soifer, H.S. / Corum, D. / Leoni, M. / Dale, S. / Fathi, A.T. |
 External links | Lancet Oncol / PubMed:39362248 |
| Methods | X-ray diffraction |
| Resolution | 1.3 - 1.57 Å |
| Structure data |  PDB-8va5:  PDB-8va6: |
| Chemicals | 
ChemComp-K5O:  ChemComp-PEG:  ChemComp-PG4:  ChemComp-EDO:  ChemComp-DMS:  ChemComp-HOH:  ChemComp-SO4: |
| Source |
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 Keywords | PROTEIN BINDING |
homo sapiens (human)