Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Optimization of Potent, Efficacious, Selective and Blood-Brain Barrier Penetrating Inhibitors Targeting EGFR Exon20 Insertion Mutations.
Journal, issue, pages	J. Med. Chem., Year 2024
Publish date	Apr 4, 2024 (structure data deposition date)
Authors	Thomson, C. / Braybrooke, E. / Colclough, N. / Davies, N.L. / Floc'h, N. / Greenwood, R. / Guerot, C. / Hargreaves, D. / Johnstrom, P. / Khurana, P. ...Thomson, C. / Braybrooke, E. / Colclough, N. / Davies, N.L. / Floc'h, N. / Greenwood, R. / Guerot, C. / Hargreaves, D. / Johnstrom, P. / Khurana, P. / Kostomiris, D.H. / Li, S. / Lister, A. / Lorthioir, O. / Martin, S. / McCoull, W. / McLean, N.J. / McWilliams, L. / Orme, J.P. / Packer, M.J. / Pearson, S. / Swaih, A.M. / Tentarelli, S. / Tucker, M.J. / Ward, R.A. / Wilkinson, S. / Winlow, P. / Wood, I.L.
External links	J. Med. Chem. / PubMed:39340451
Methods	X-ray diffraction
Resolution	2.435 - 3.019 Å
Structure data	PDB-9ews: Optimisation of Potent, Efficacious, Selective and Blood-Brain Barrier Penetrating Inhibitors Targeting EGFR Exon20 Insertion Mutations Method: X-RAY DIFFRACTION / Resolution: 2.435 Å PDB-9ewt: Optimisation of Potent, Efficacious, Selective and Blood-Brain Barrier Penetrating Inhibitors Targeting EGFR Exon20 Insertion Mutations Method: X-RAY DIFFRACTION / Resolution: 3.019 Å
Chemicals	PDB-1h7n: SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH LAEVULINIC ACID AT 1.6 A RESOLUTION ChemComp-IOD: IODIDE ION ChemComp-HOH: WATER PDB-1h7o: SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 5-AMINOLAEVULINIC ACID AT 1.7 A RESOLUTION
Source	homo sapiens (human)
Keywords	SIGNALING PROTEIN / EGFR / exon20 insertion / NPG