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TitleAn Innovative Inhibitor with a New Chemical Moiety Aimed at Biliverdin IX beta Reductase for Thrombocytopenia and Resilient against Cellular Degradation.
Journal, issue, pagesPharmaceutics, Vol. 16, Year 2024
Publish dateJul 19, 2023 (structure data deposition date)
AuthorsJung, H.M. / Ha, J.H. / Dela Cerna, M.V.C. / Burlison, J.A. / Choi, J. / Kim, B.R. / Bang, J.K. / Ryu, K.S. / Lee, D.
External linksPharmaceutics / PubMed:39339186
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-8k4k:
Crystal structure of human Biliverdin IX-beta reductase B with Olsalazine carbon derivative
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE


ChemComp, No image

ChemComp-VE2:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE/INHIBITOR / platelets / NADP / OXIDOREDUCTASE-INHIBITOR COMPLEX

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