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TitleCrystal structure of Alzheimer's disease phospholipase D3 provides a molecular basis for understanding its normal and pathological functions.
Journal, issue, pagesFebs J., Vol. 291, Page 5398-5419, Year 2024
Publish dateDec 1, 2023 (structure data deposition date)
AuthorsIshii, K. / Hermans, S.J. / Georgopoulou, M.E. / Nero, T.L. / Hancock, N.C. / Crespi, G.A.N. / Gorman, M.A. / Gooi, J.H. / Parker, M.W.
External linksFebs J. / PubMed:39325669
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-8v5t:
Crystal structure of Alzheimers disease phospholipase D3
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN / Exonuclease / Alzheimer's Disease

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