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-Structure paper
Title | Crystallographic and Selectivity Studies on the Approved HIF Prolyl Hydroxylase Inhibitors Desidustat and Enarodustat. |
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Journal, issue, pages | Chemmedchem, Vol. 19, Page e202400504-e202400504, Year 2024 |
Publish date | Jun 21, 2024 (structure data deposition date) |
![]() | Corner, T.P. / Salah, E. / Tumber, A. / Kaur, S. / Nakashima, Y. / Allen, M.D. / Schnaubelt, L.I. / Fiorini, G. / Brewitz, L. / Schofield, C.J. |
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Methods | X-ray diffraction |
Resolution | 2.16 - 2.2 Å |
Structure data | ![]() PDB-9fsn: ![]() PDB-9iif: |
Chemicals | ![]() ChemComp-MN: ![]() PDB-1if7: ![]() ChemComp-HOH: ![]() ChemComp-SO4: ![]() PDB-1l2l: ![]() ChemComp-ZN: |
Source |
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![]() | OXIDOREDUCTASE / FIH / oxygenase / Complex / inhibitor / factor-inhibiting hypoxia-inducible factor / 2OG dependent dioxygenase |