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TitleA Bioorthogonal Precision Tool for Human N -Acetylglucosaminyltransferase V.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 146, Page 26707-26718, Year 2024
Publish dateApr 28, 2024 (structure data deposition date)
AuthorsLiu, Y. / Bineva-Todd, G. / Meek, R.W. / Mazo, L. / Piniello, B. / Moroz, O. / Burnap, S.A. / Begum, N. / Ohara, A. / Roustan, C. ...Liu, Y. / Bineva-Todd, G. / Meek, R.W. / Mazo, L. / Piniello, B. / Moroz, O. / Burnap, S.A. / Begum, N. / Ohara, A. / Roustan, C. / Tomita, S. / Kjaer, S. / Polizzi, K. / Struwe, W.B. / Rovira, C. / Davies, G.J. / Schumann, B.
External linksJ. Am. Chem. Soc. / PubMed:39287665
MethodsX-ray diffraction
Resolution1.97 Å
Structure data

PDB-9f5h:
Crystal structure of MGAT5 bump-and-hole mutant in complex with UDP and M592
Method: X-RAY DIFFRACTION / Resolution: 1.97 Å

Chemicals

ChemComp-UDP:
URIDINE-5'-DIPHOSPHATE / UDP*YM

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-MAN:
alpha-D-mannopyranose

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Bump and hole / bioorthogonal tag

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