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TitlePhosphorylation of tau at a single residue inhibits binding to the E3 ubiquitin ligase, CHIP.
Journal, issue, pagesNat Commun, Vol. 15, Page 7972-7972, Year 2024
Publish dateJan 26, 2023 (structure data deposition date)
AuthorsNadel, C.M. / Pokhrel, S. / Wucherer, K. / Oehler, A. / Thwin, A.C. / Basu, K. / Callahan, M.D. / Southworth, D.R. / Mordes, D.A. / Craik, C.S. / Gestwicki, J.E.
External linksNat Commun / PubMed:39266525
MethodsX-ray diffraction
Resolution1.84839139202 Å
Structure data

PDB-8fyu:
Crystal structure of the human CHIP-TPR domain in complex with a 10mer acetylated tau peptide
Method: X-RAY DIFFRACTION / Resolution: 1.84839139202 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE / E3 ligase / ligand / TPR domain

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