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Title | Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models. |
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Journal, issue, pages | Sci Transl Med, Vol. 16, Page eado4463-eado4463, Year 2024 |
Publish date | Feb 21, 2024 (structure data deposition date) |
Authors | Dejoux, A. / Zhu, Q. / Ganneau, C. / Goff, O.R. / Godon, O. / Lemaitre, J. / Relouzat, F. / Huetz, F. / Sokal, A. / Vandenberghe, A. ...Dejoux, A. / Zhu, Q. / Ganneau, C. / Goff, O.R. / Godon, O. / Lemaitre, J. / Relouzat, F. / Huetz, F. / Sokal, A. / Vandenberghe, A. / Pecalvel, C. / Hunault, L. / Derenne, T. / Gillis, C.M. / Iannascoli, B. / Wang, Y. / Rose, T. / Mertens, C. / Nicaise-Roland, P. / England, P. / Mahevas, M. / de Chaisemartin, L. / Le Grand, R. / Letscher, H. / Saul, F. / Pissis, C. / Haouz, A. / Reber, L.L. / Chappert, P. / Jonsson, F. / Ebo, D.G. / Millot, G.A. / Bay, S. / Chollet-Martin, S. / Gouel-Cheron, A. / Bruhns, P. |
External links | Sci Transl Med / PubMed:39259810 |
Methods | X-ray diffraction |
Resolution | 1.6 - 1.7 Å |
Structure data | PDB-8s4h: PDB-8s4k: |
Chemicals | ChemComp-RBR: ChemComp-HOH: ChemComp-EPE: |
Source |
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Keywords | IMMUNE SYSTEM / NeuroMuscular Blocking Agents Rocuronium-induced anaphylaxis |