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TitleCD28 hinge used in chimeric antigen receptor (CAR) T-cells exhibits local structure and conformational exchange amidst global disorder.
Journal, issue, pagesCommun Biol, Vol. 7, Page 1072-1072, Year 2024
Publish dateFeb 21, 2024 (structure data deposition date)
AuthorsFolimonova, V. / Chen, X. / Negi, H. / Schwieters, C.D. / Li, J. / Byrd, R.A. / Taylor, N. / Youkharibache, P. / Walters, K.J.
External linksCommun Biol / PubMed:39217198
MethodsNMR (solution)
Structure data

PDB-8w2v:
Solution Structure of the CD28 hinge used in chimeric antigen receptor (CAR) T-cells
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / CAR-T / CD28 / immunotherapy / intrinsic disorder

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