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| Title | Tumor-derived RHOA mutants interact with effectors in the GDP-bound state. |
|---|---|
| Journal, issue, pages | Nat Commun, Vol. 15, Page 7176-7176, Year 2024 |
| Publish date | Jan 5, 2023 (structure data deposition date) |
Authors | Lin, Y. / Ramelot, T.A. / Senyuz, S. / Gursoy, A. / Jang, H. / Nussinov, R. / Keskin, O. / Zheng, Y. |
External links | Nat Commun / PubMed:39169042 |
| Methods | X-ray diffraction |
| Resolution | 1.4 - 1.47 Å |
| Structure data | ![]() PDB-8fpw: ![]() PDB-8fpx: |
| Chemicals | ![]() ChemComp-GDP: ![]() ChemComp-MG: ![]() ChemComp-DIO: ![]() ChemComp-HOH: |
| Source |
|
Keywords | SIGNALING PROTEIN / Small G proteins / GTPase / fast-cycling mutant / Hydrolase / A161P |
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homo sapiens (human)
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